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Of mice, men, and inflammation
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Of mice, men, and inflammation

Anje Cauwels ; Benjamin Vandendriessche ; Peter Brouckaert

Proceedings of the National Academy of Sciences, 2013-08-20, Vol.110 (34), p.E3150-E3150 [Rivista Peer Reviewed]

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Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice
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Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice

Thoonen, Robrecht ; Cauwels, Anje ; Decaluwe, Kelly ; Geschka, Sandra ; Tainsh, Robert E ; Delanghe, Joris ; Hochepied, Tino ; De Cauwer, Lode ; Rogge, Elke ; Voet, Sofie ; Sips, Patrick ; Karas, Richard H ; Bloch, Kenneth D ; Vuylsteke, Marnik ; Stasch, Johannes-Peter ; Van de Voorde, Johan ; Buys, Emmanuel S ; Brouckaert, Peter

Nature communications, 2015-10-07, Vol.6 (1), p.8482 [Rivista Peer Reviewed]

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Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2
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Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2

Cuvelier, Claude ; Waeytens, Anouk ; Brouckaert, Peter ; Cauwels, Anje ; Janssen, Ben

Nature Immunology, 2003-04, Vol.4 (4), p.387-393 [Rivista Peer Reviewed]

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The Soluble Guanylate Cyclase Activator BAY 58-2667 Protects against Morbidity and Mortality in Endotoxic Shock by Recoupling Organ Systems
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The Soluble Guanylate Cyclase Activator BAY 58-2667 Protects against Morbidity and Mortality in Endotoxic Shock by Recoupling Organ Systems

Vandendriessche, Benjamin ; Rogge, Elke ; Goossens, Vera ; Vandenabeele, Peter ; Stasch, Johannes-Peter ; Brouckaert, Peter ; Cauwels, Anje ; Schmidt, Harald H. H. W

PloS one, 2013-08-28, Vol.8 (8), p.e72155 [Rivista Peer Reviewed]

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Transcriptome analysis in patients with chronic kidney disease on hemodialysis disclosing a key role for CD16+CX3CR1+ monocytes
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Transcriptome analysis in patients with chronic kidney disease on hemodialysis disclosing a key role for CD16+CX3CR1+ monocytes

Schepers, Eva ; Houthuys, Erica ; Dhondt, Annemieke ; De Meyer, Grim ; Neirynck, Nathalie ; Bernaert, Pascale ; Van den Bergh, Rafael ; Brouckaert, Peter ; Vanholder, Raymond ; Glorieux, Griet ; Song, Qing

PloS one, 2015, Vol.10 (4), p.e0121750 [Rivista Peer Reviewed]

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Reactive oxygen species and small-conductance calcium-dependent potassium channels are key mediators of inflammation-induced hypotension and shock
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Reactive oxygen species and small-conductance calcium-dependent potassium channels are key mediators of inflammation-induced hypotension and shock

Cauwels, Anje ; Rogge, Elke ; Janssen, Ben ; Brouckaert, Peter

Journal of molecular medicine (Berlin, Germany), 2010, Vol.88 (9), p.921-930 [Rivista Peer Reviewed]

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7
SERCA Cys674 sulphonylation and inhibition of L-type Ca2+ influx contribute to cardiac dysfunction in endotoxemic mice, independent of cGMP synthesis
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SERCA Cys674 sulphonylation and inhibition of L-type Ca2+ influx contribute to cardiac dysfunction in endotoxemic mice, independent of cGMP synthesis

Hobai, Ion A ; Buys, Emmanuel S ; Morse, Justin C ; Edgecomb, Jessica ; Weiss, Eric H ; Armoundas, Antonis A ; Hou, Xiuyun ; Khandelwal, Alok R ; Siwik, Deborah A ; Brouckaert, Peter ; Cohen, Richard A ; Colucci, Wilson S

American journal of physiology. Heart and circulatory physiology, 2013-10-15, Vol.305 (8), p.H1189-H1200 [Rivista Peer Reviewed]

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8
Soluble guanylate cyclase α1-deficient mice: a novel murine model for primary open angle glaucoma
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Soluble guanylate cyclase α1-deficient mice: a novel murine model for primary open angle glaucoma

Buys, Emmanuel S ; Ko, Yu-Chieh ; Alt, Clemens ; Hayton, Sarah R ; Jones, Alexander ; Tainsh, Laurel T ; Ren, Ruiyi ; Giani, Andrea ; Clerté, Maeva ; Abernathy, Emma ; Tainsh, Robert E T ; Oh, Dong-Jin ; Malhotra, Rajeev ; Arora, Pankaj ; de Waard, Nadine ; Yu, Binglan ; Turcotte, Raphael ; Nathan, Daniel ; Scherrer-Crosbie, Marielle ; Loomis, Stephanie J ; Kang, Jae H ; Lin, Charles P ; Gong, Haiyan ; Rhee, Douglas J ; Brouckaert, Peter ; Wiggs, Janey L ; Gregory, Meredith S ; Pasquale, Louis R ; Bloch, Kenneth D ; Ksander, Bruce R ; Libby, Richard

PloS one, 2013, Vol.8 (3), p.e60156 [Rivista Peer Reviewed]

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The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioning
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The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioning

Sips, Patrick Y ; Brouckaert, Peter ; Ichinose, Fumito

Basic Research in Cardiology, 2011-07, Vol.106 (4), p.635-643 [Rivista Peer Reviewed]

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Citrulline Supplementation Improves Organ Perfusion and Arginine Availability under Conditions with Enhanced Arginase Activity
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Citrulline Supplementation Improves Organ Perfusion and Arginine Availability under Conditions with Enhanced Arginase Activity

Wijnands, Nina ; Meesters, Dennis M ; van Barneveld, Kevin W. Y ; Visschers, Ruben G. J ; Briede, Jacob J ; Vandeniessche, Benjamin ; van Eijk, Hans M. H ; Bessems, Babs A. F. M ; van den Hoven, Nadine ; von Wintersdorff, Christian J. H ; Brouckaert, Peter ; Bouvy, Nicole D ; Lamers, Wouter H ; Cauwels, Anje ; Poeze, Martijn

Nutrients, 2015-07, Vol.7 (7), p.5217-5238 [Rivista Peer Reviewed]

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