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Heterodimeric JAK-STAT Activation as a Mechanism of Persistence to JAK2 Inhibitor Therapy

Koppikar, Priya ; Bhagwat, Neha ; Kilpivaara, Outi ; Manshouri, Taghi ; Adli, Mazhar ; Hricik, Todd ; Liu, Fan ; Saunders, Lindsay M ; Mullally, Ann ; Abdel-Wahab, Omar ; Leung, Laura ; Weinstein, Abby ; Marubayashi, Sachie ; Goel, Aviva ; Gönen, Mithat ; Estrov, Zeev ; Ebert, Benjamin L ; Chiosis, Gabriela ; Nimer, Stephen D ; Bernstein, Bradley E ; Verstovsek, Srdan ; Levine, Ross L

Nature, 2012, Vol.489(7414), p.155-159 [Rivista Peer Reviewed]

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Synthesis of 6- and 7-propargyloxy derivatives of 4-(3-fluoroanilino)-quinazoline

Pham, Helen Trinh ; Hanson, Robert N ; Olmsted, Sandra L ; Kozhushnyan, Anton ; Visentin, Adam ; Weglinsky, Paul J ; Massero, Chris ; Bailey, Kristen

Tetrahedron Letters, 2011, Vol.52(10), pp.1053-1056 [Rivista Peer Reviewed]

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Differential action of small molecule HER kinase inhibitors on receptor heterodimerization: Therapeutic implications

Sánchez‐Martín, M. ; Pandiella, A.

International Journal of Cancer, 01 July 2012, Vol.131(1), pp.244-252 [Rivista Peer Reviewed]

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Tumor‐Targeting of EGFR Inhibitors by Hypoxia‐Mediated Activation

Karnthaler‐Benbakka, Claudia ; Groza, Diana ; Kryeziu, Kushtrim ; Pichler, Verena ; Roller, Alexander ; Berger, Walter ; Heffeter, Petra ; Kowol, Christian R.

Angewandte Chemie International Edition, 17 November 2014, Vol.53(47), pp.12930-12935 [Rivista Peer Reviewed]

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Estimations of the increasing prevalence and plateau prevalence of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy

Huang, Xuelin ; Cortes, Jorge ; Kantarjian, Hagop

Cancer, 15 June 2012, Vol.118(12), pp.3123-3127 [Rivista Peer Reviewed]

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Impact of tyrosine kinase inhibitors on the incidence of brain metastasis in metastatic renal cell carcinoma

Verma, Jonathan ; Jonasch, Eric ; Allen, Pamela ; Tannir, Nizar ; Mahajan, Anita

Cancer, 01 November 2011, Vol.117(21), pp.4958-4965 [Rivista Peer Reviewed]

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HCVAD plus imatinib or dasatinib in lymphoid blastic phase chronic myeloid leukemia

Strati, Paolo ; Kantarjian, Hagop ; Thomas, Deborah ; O' Brien, Susan ; Konoplev, Sergej ; Jorgensen, Jeffrey L. ; Luthra, Raja ; Abruzzo, Lynne ; Jabbour, Elias ; Quintas‐Cardama, Alfonso ; Borthakur, Gautam ; Faderl, Stefan ; Ravandi, Farhad ; Cortes, Jorge

Cancer, 01 February 2014, Vol.120(3), pp.373-380 [Rivista Peer Reviewed]

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Conditional survival in patients with chronic myeloid leukemia in chronic phase in the era of tyrosine kinase inhibitors

Sasaki, Koji ; Kantarjian, Hagop M. ; Jain, Preetesh ; Jabbour, Elias J. ; Ravandi, Farhad ; Konopleva, Marina ; Borthakur, Gautam ; Takahashi, Koichi ; Pemmaraju, Naveen ; Daver, Naval ; Pierce, Sherry A. ; O' Brien, Susan M. ; Cortes, Jorge E.

Cancer, 15 January 2016, Vol.122(2), pp.238-248 [Rivista Peer Reviewed]

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Call for Action: Invasive Fungal Infections Associated With Ibrutinib and Other Small Molecule Kinase Inhibitors Targeting Immune Signaling Pathways

Chamilos, Georgios ; Lionakis, Michail S ; Kontoyiannis, Dimitrios P

Clinical Infectious Diseases, 2018, Vol. 66(1), pp.140-148 [Rivista Peer Reviewed]

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Ongoing Screening and Treatment to Potentially Reduce Tyrosine Kinase Inhibitor-Related Fatigue in Renal Cell Carcinoma

Anand, Deepa ; Escalante, Carmen P

Journal of Pain and Symptom Management, July 2015, Vol.50(1), pp.108-117 [Rivista Peer Reviewed]

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di questo autore:

  1. Kantarjian, Hagop
  2. Cortes, Jorge
  3. Jabbour, Elias
  4. Ravandi, Farhad
  5. Baccarani, Michele

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