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Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk

Papandreou, Christopher ; Babio, Nancy ; Díaz-López, Andrés ; Martínez-González, Miguel Á ; Becerra-Tomas, Nerea ; Corella, Dolores ; Schröder, Helmut ; Romaguera, Dora ; Vioque, Jesús ; Alonso-Gómez, Ángel M

Nutrients, 01 April 2019, Vol.11(4) [Rivista Peer Reviewed]

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  • Titolo:
    Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
  • Autore: Papandreou, Christopher ; Babio, Nancy ; Díaz-López, Andrés ; Martínez-González, Miguel Á ; Becerra-Tomas, Nerea ; Corella, Dolores ; Schröder, Helmut ; Romaguera, Dora ; Vioque, Jesús ; Alonso-Gómez, Ángel M
  • Note di contenuto: The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.
  • Fa parte di: Nutrients, 01 April 2019, Vol.11(4)
  • Soggetti: Actigraphy ; Serum Uric Acid ; Serum Uric Acid to Creatinine Ratio ; Sleep Duration
  • Lingua: Inglese
  • Tipo: Articolo
  • Identificativo: E-ISSN: 2072-6643 ; PMID: 30939748 Version:1 ; DOI: 10.3390/nu11040761

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