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Validation of the BAP-65 score for prediction of in-hospital death or use of mechanical ventilation in patients presenting to the emergency department with an acute exacerbation of COPD: a retrospective multi-center study from the Italian Society of Emergency Medicine (SIMEU)

Germini, Federico ; Veronese, Giacomo ; Marcucci, Maura ; Coen, Daniele ; Ardemagni, Deborah ; Montano, Nicola ; Fabbri, Andrea

European journal of internal medicine, March 2019, Vol.61, pp.62-68 [Rivista Peer Reviewed]

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  • Titolo:
    Validation of the BAP-65 score for prediction of in-hospital death or use of mechanical ventilation in patients presenting to the emergency department with an acute exacerbation of COPD: a retrospective multi-center study from the Italian Society of Emergency Medicine (SIMEU)
  • Autore: Germini, Federico ; Veronese, Giacomo ; Marcucci, Maura ; Coen, Daniele ; Ardemagni, Deborah ; Montano, Nicola ; Fabbri, Andrea
  • Note di contenuto: Exacerbations of chronic obstructive pulmonary disease (COPDE) frequently require hospitalizations, may necessitate of invasive mechanical ventilation (IMV), and are associated with a remarkable in-hospital mortality. The BAP-65 score is a risk assessment model (RAM) based on simple variables, that has been proposed for the prediction of these adverse outcomes in patients with COPDE. If showed to be accurate, the BAP-65 RAM might be used to guide the patients management, in terms of destination and treatment. We conducted a retrospective, multicentre, chart-review study, on patients attending the ED for a COPDE during 2014. The aim of the study was the validation of the BAP-65 RAM for the prediction of in-hospital death or use of IMV (composite primary outcome). We assessed the discrimination and the prognostic performance of the BAP-65 RAM. We enrolled 2908 patients from 20 centres across Italy. The mean (standard deviation) age was 76 (11) years, and 38% of patients were female. The composite...
  • Fa parte di: European journal of internal medicine, March 2019, Vol.61, pp.62-68
  • Soggetti: Chronic Obstructive ; Emergency Service, Hospital ; Prognosis ; Pulmonary Disease ; Risk
  • Lingua: Inglese
  • Tipo: Articolo
  • Identificativo: E-ISSN: 1879-0828 ; PMID: 30391167 Version:1 ; DOI: 10.1016/j.ejim.2018.10.018
  • Fonte: MEDLINE/PubMed (U.S. National Library of Medicine)

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