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The relationship between impulsivity and impulse control disorders in Parkinson's disease

Isaias, Ioannis U ; Siri, Chiara ; Cilia, Roberto ; De Gaspari, Danilo ; Pezzoli, Gianni ; Antonini, Angelo

Movement disorders : official journal of the Movement Disorder Society, 15 February 2008, Vol.23(3), pp.411-5 [Rivista Peer Reviewed]

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  • Titolo:
    The relationship between impulsivity and impulse control disorders in Parkinson's disease
  • Autore: Isaias, Ioannis U ; Siri, Chiara ; Cilia, Roberto ; De Gaspari, Danilo ; Pezzoli, Gianni ; Antonini, Angelo
  • Note di contenuto: A range of behaviors presumed to be related to dopaminergic medications have been recently recognized in Parkinson's disease (PD). We evaluated 50 consecutive cognitively intact PD patients on stable dopamine agonist and levodopa therapy and 100 healthy controls for compulsive sexual behavior, compulsive buying, or intermittent explosive disorders assessed by the Minnesota Impulsive Disorders Interview (MIDI), pathological gambling (South Oaks Gambling Screen, SOGS), impulsivity (Barratt Impulsiveness Scale), compulsivity (Maudsley obsessional-compulsive inventory), and depression scores (Geriatric Depression Scale). Overall 28% PD (14/50) and 20% healthy controls (20/100) reported at least one abnormal behavior at MIDI or pathological SOGS score. PD patients had higher scores than controls for impulsivity (P = 0.006), compulsivity (P < 0.001), and depression (P < 0.001). There was no correlation between impulsivity, compulsivity, and depression scores in PD. Male gender and higher impulsivity...
  • Fa parte di: Movement disorders : official journal of the Movement Disorder Society, 15 February 2008, Vol.23(3), pp.411-5
  • Soggetti: Compulsive Behavior -- Etiology ; Disruptive, Impulse Control, and Conduct Disorders -- Complications ; Parkinson Disease -- Complications
  • Lingua: Inglese
  • Tipo: Articolo
  • Identificativo: E-ISSN: 1531-8257 ; PMID: 18067187 Version:1

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